The Mississippi River, among many names, is known as “The Backbone of America,” and has played a major role in shaping the lives of the Indigenous people, European colonizers, and others throughout the rest of the nation and the world. The river flows approximately 2,340 miles beginning at its source at Lake Itasca in Clearwater County, Minnesota through the center of the continental United States to 100 miles downstream of New Orleans, Louisiana in the Gulf of Mexico. Its tributaries (e.g., the Arkansas River, the Illinois River, the Missouri River, the Ohio River, and the Red River) reach from east and west across much of the United States of America. Prior to the emergence of trains in the late nineteenth century, the Mississippi River served as a major throughway to transport cargo and passengers destined for both domestic destinations and for larger ships where captains would continue their voyage out to ocean and into ports located in other parts of the world.